![]() ![]() ![]() As the alveolar disease progresses, respiratory failure might develop and death may follow. The density of ACE2 in each tissue correlates with the severity of the disease in that tissue and some have suggested that decreasing ACE2 activity might be protective, though another view is that increasing ACE2 using Angiotensin II receptor blocker medications could be protective and that these hypotheses need to be tested. The virus uses a special surface glycoprotein, called "spike", to connect to ACE2 and enter the host cell. The lungs are the organs most affected by COVID-19 because the virus accesses host cells via the enzyme ACE2, which is most abundant in the type II alveolar cells of the lungs. ![]() The virus has also been found in faeces, but as of March 2020 it is unknown whether transmission through faeces is possible, and the risk is expected to be low. The virus can remain viable for up to three days on plastic and stainless steel, and for three hours in aerosols. It is primarily spread between people via respiratory droplets from coughs and sneezes. The disease is caused by the virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), previously referred to as the 2019 novel coronavirus (2019-nCoV). The incubation period for COVID-19 is typically five to six days but may range from two to fourteen days Cause of COVID 19 In some, the disease may progress to pneumonia, multi-organ failure, and death.Īs is common with infections, there is a delay from when a person is infected with the virus to when they develop symptoms, known as the incubation period. Symptoms such as nausea, vomiting, and diarrhoea are seen in a minority of cases, and some of the initial cases in China presented with only chest tightness and palpitations. Less commonly, upper respiratory symptoms such as sneezing, runny nose, or sore throat may be seen. Emergency symptoms including difficulty breathing, persistent chest pain or pressure, confusion, difficulty waking, and bluish face or lips immediate medical attention is advised if these symptoms are present. "We will review this decision in the next 3-4 days," he had said on Tuesday after a meeting of the state cabinet.Although those infected with the virus may be asymptomatic, many develop flu-like symptoms including fever, cough, and shortness of breath. Public transport, especially buses and local trains in Mumbai will also continue to operate at full capacity. Maharashtra chief minister Uddhav Thackeray reassured citizens that government offices and essential services will function. The wife of the deceased, who has also tested positive, is undergoing treatment and her condition is said to be stable. Unfortunately, he passed away this morning," Dr Daksha Shah, deputy health officer of Brihanmumbai Municipal Corporation had told reporters on Tuesday. However, as compromised heart function and septicemia set in, we put him back on the ventilator. He was stable till Monday night and doctors tried to wean him off the ventilator. “The patient had a history of chronic high blood pressure, pneumonia and inflammation of heart muscles. On Tuesday, COVID-19 claimed its first victim in Mumbai, prompting the state government to ramp up testing and isolation facilities and take help from private hospitals and laboratories even as it stopped short of restricting public transport.Ī 63-year-old man, who had travelled to Dubai with his wife and son, died at Kasturba Hospital in the city due to complications arising from the novel coronavirus infection. ![]()
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